Safe ex vivo coronary angiography with isosmotic contrast agent

Iodixanol, a new isosmotic nonionic contrast agent compared with iohexol in cardiac angiography.

Iodixanol, a new ratio 6 nonionic iodinated contrast agent with an osmolality equal to serum, was compared with iohexol in a randomized, double-blind, parallel study. Two hundred patients undergoing elective diagnostic cardiac angiography were randomized to iodixanol (n = 101) or iohexol (n = 99). There were no differences noted between the 2 agents in the mean changes in systolic or diastolic ...

Triphasic Contrast Agent Injection in 64-MDCT Coronary Artery Angiography

Purpose: To evaluate image quality and cardiovascular enhancement after triphasic injection in 64-slice-CT coronary angiography (c-CTA). Methods: c-CTA of twenty-two asymptomatic patients following triphasic injection (65ml-contrast bolus + mixed 30mlcontrast and 20ml-saline bolus + 50ml-saline chaser) were retrospectively reviewed. Attenuation in the great vessels, cardiac chambers, and corona...

Coronary Angiography and Contrast-Induced Nephropathy

Safe limits of contrast vary with hydration volume for prevention of contrast-induced nephropathy after coronary angiography among patients with a relatively low risk of contrast-induced nephropathy.

BACKGROUND Few studies have investigated the safe limits of contrast to prevent contrast-induced nephropathy (CIN) based on hydration data. We aimed to investigate the relative safe maximum contrast volume adjusted for hydration volume in a population with a relatively low risk of CIN. METHODS AND RESULTS The ratios of contrast volume-to-creatinine clearance (V/CrCl) and hydration volume to b...

atorvastatin and prevention of contrast induced nephropathy following coronary angiography

background: contrast induced nephropathy (cin) is one of the most common complications after radiographic procedures using intravascular radiocontrast media. the aim of the current study was to assess the effect of atorvastatin on prevention of cin in patients undergoing coronary angiography. materials and methods: in a clinical trial study, 200 patients referred for angiography were randomly d...